POLH protein (Canis lupus familiaris) - STRING interaction network

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[Homology]

Score

POLH

DNA polymerase eta. (712 aa)

Predicted Functional Partners:

AFF3

0.983

PCNA

0.982

RAD18

0.968

REV3L

0.937

POLI

0.868

RPS27A

0.864

OGG1

0.845

MAD2L2

0.829

UBA52

0.808

UBE2V2

0.787

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFF3	MAD2L2	ENSCAFP00000052865	ENSCAFP00000024383	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Mitotic arrest deficient 2 like 2.	0.991
AFF3	OGG1	ENSCAFP00000052865	ENSCAFP00000052444	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	8-oxoguanine DNA glycosylase.	0.557
AFF3	PCNA	ENSCAFP00000052865	ENSCAFP00000009045	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.952
AFF3	POLH	ENSCAFP00000052865	ENSCAFP00000002810	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	DNA polymerase eta.	0.983
AFF3	POLI	ENSCAFP00000052865	ENSCAFP00000000218	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	DNA polymerase iota.	0.955
AFF3	RAD18	ENSCAFP00000052865	ENSCAFP00000008290	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	RAD18 E3 ubiquitin protein ligase.	0.765
AFF3	REV3L	ENSCAFP00000052865	ENSCAFP00000051058	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.978
AFF3	RPS27A	ENSCAFP00000052865	ENSCAFP00000031429	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Ubiquitin-like domain-containing protein.	0.805
AFF3	UBA52	ENSCAFP00000052865	ENSCAFP00000021714	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]	0.779
AFF3	UBE2V2	ENSCAFP00000052865	ENSCAFP00000038211	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	Ubiquitin conjugating enzyme E2 V2.	0.619
MAD2L2	AFF3	ENSCAFP00000024383	ENSCAFP00000052865	Mitotic arrest deficient 2 like 2.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.991
MAD2L2	PCNA	ENSCAFP00000024383	ENSCAFP00000009045	Mitotic arrest deficient 2 like 2.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.771
MAD2L2	POLH	ENSCAFP00000024383	ENSCAFP00000002810	Mitotic arrest deficient 2 like 2.	DNA polymerase eta.	0.829
MAD2L2	POLI	ENSCAFP00000024383	ENSCAFP00000000218	Mitotic arrest deficient 2 like 2.	DNA polymerase iota.	0.857
MAD2L2	RAD18	ENSCAFP00000024383	ENSCAFP00000008290	Mitotic arrest deficient 2 like 2.	RAD18 E3 ubiquitin protein ligase.	0.573
MAD2L2	REV3L	ENSCAFP00000024383	ENSCAFP00000051058	Mitotic arrest deficient 2 like 2.	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.999
MAD2L2	RPS27A	ENSCAFP00000024383	ENSCAFP00000031429	Mitotic arrest deficient 2 like 2.	Ubiquitin-like domain-containing protein.	0.506
MAD2L2	UBA52	ENSCAFP00000024383	ENSCAFP00000021714	Mitotic arrest deficient 2 like 2.	Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...]	0.500
MAD2L2	UBE2V2	ENSCAFP00000024383	ENSCAFP00000038211	Mitotic arrest deficient 2 like 2.	Ubiquitin conjugating enzyme E2 V2.	0.592
OGG1	AFF3	ENSCAFP00000052444	ENSCAFP00000052865	8-oxoguanine DNA glycosylase.	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family.	0.557