STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NFXL1Nuclear transcription factor, X-box binding like 1. (914 aa)    
Predicted Functional Partners:
CNGA1
cGMP-gated cation channel alpha-1; Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.
      
 0.880
AGBL1
ATP/GTP binding protein like 1.
      
 0.770
SLAIN2
SLAIN motif family member 2.
    
 
 0.764
OCIAD1
OCIA domain containing 1.
      
 0.686
TEC
Tyrosine-protein kinase.
   
  
 0.674
ZNF451
Zinc finger protein 451.
   
  
 0.672
BEND4
BEN domain containing 4.
      
 0.648
LRRC66
Leucine rich repeat containing 66.
      
 0.646
PDCL2
Phosducin like 2.
      
 0.635
NIPAL1
NIPA like domain containing 1.
      
 0.630
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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