GTPBP2 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

GTPBP2

GTP binding protein 2. (602 aa)

Predicted Functional Partners:

NRIP2

0.820

RCBTB2

0.708

NPHP3

0.696

LAMC3

0.673

ALDH4A1

0.670

MRRF

0.668

AP4M1

0.629

RDH11

0.628

TCP11L2

0.609

RTN4

0.598

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH4A1	GTPBP2	ENSCAFP00000039790	ENSCAFP00000002822	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	GTP binding protein 2.	0.670
ALDH4A1	LAMC3	ENSCAFP00000039790	ENSCAFP00000040626	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Laminin subunit gamma 3.	0.617
ALDH4A1	NPHP3	ENSCAFP00000039790	ENSCAFP00000066560	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Nephrocystin 3.	0.670
ALDH4A1	TCP11L2	ENSCAFP00000039790	ENSCAFP00000002751	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	T-complex 11 like 2.	0.426
AP4M1	GTPBP2	ENSCAFP00000045740	ENSCAFP00000002822	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (By similarity). It is also involved in protein sorting to the basolateral membrane in epithelial cells and [...]	GTP binding protein 2.	0.629
GTPBP2	ALDH4A1	ENSCAFP00000002822	ENSCAFP00000039790	GTP binding protein 2.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.670
GTPBP2	AP4M1	ENSCAFP00000002822	ENSCAFP00000045740	GTP binding protein 2.	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (By similarity). It is also involved in protein sorting to the basolateral membrane in epithelial cells and [...]	0.629
GTPBP2	LAMC3	ENSCAFP00000002822	ENSCAFP00000040626	GTP binding protein 2.	Laminin subunit gamma 3.	0.673
GTPBP2	MRRF	ENSCAFP00000002822	ENSCAFP00000060290	GTP binding protein 2.	Mitochondrial ribosome recycling factor.	0.668
GTPBP2	NPHP3	ENSCAFP00000002822	ENSCAFP00000066560	GTP binding protein 2.	Nephrocystin 3.	0.696
GTPBP2	NRIP2	ENSCAFP00000002822	ENSCAFP00000023008	GTP binding protein 2.	Nuclear receptor interacting protein 2.	0.820
GTPBP2	RCBTB2	ENSCAFP00000002822	ENSCAFP00000006607	GTP binding protein 2.	RCC1 and BTB domain containing protein 2.	0.708
GTPBP2	RDH11	ENSCAFP00000002822	ENSCAFP00000064481	GTP binding protein 2.	Retinol dehydrogenase 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.628
GTPBP2	RTN4	ENSCAFP00000002822	ENSCAFP00000039140	GTP binding protein 2.	Reticulon.	0.598
GTPBP2	TCP11L2	ENSCAFP00000002822	ENSCAFP00000002751	GTP binding protein 2.	T-complex 11 like 2.	0.609
LAMC3	ALDH4A1	ENSCAFP00000040626	ENSCAFP00000039790	Laminin subunit gamma 3.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.617
LAMC3	GTPBP2	ENSCAFP00000040626	ENSCAFP00000002822	Laminin subunit gamma 3.	GTP binding protein 2.	0.673
LAMC3	NPHP3	ENSCAFP00000040626	ENSCAFP00000066560	Laminin subunit gamma 3.	Nephrocystin 3.	0.665
MRRF	GTPBP2	ENSCAFP00000060290	ENSCAFP00000002822	Mitochondrial ribosome recycling factor.	GTP binding protein 2.	0.668
NPHP3	ALDH4A1	ENSCAFP00000066560	ENSCAFP00000039790	Nephrocystin 3.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.670