STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAD2L1BPMAD2L1 binding protein. (274 aa)    
Predicted Functional Partners:
TRIP13
Pachytene checkpoint protein 2 homolog; Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher- order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for [...]
    
 
 0.902
INPP5K
Inositol polyphosphate-5-phosphatase K.
    
 
 0.856
MAD1L1
Mitotic arrest deficient 1 like 1.
    
 
 0.844
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
    
 
 0.830
MAD2L1
HORMA domain-containing protein.
   
 
 0.801
ENSCAFP00000059433
HORMA domain-containing protein.
   
 
 0.801
ENSCAFP00000061810
HORMA domain-containing protein.
   
 
 0.801
LBR
Lamin B receptor.
    
   0.780
CDC20B
Cell division cycle 20B.
    
 
 0.746
CDC20
Cell division cycle 20.
    
 
 0.746
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.