STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (543 aa)    
Predicted Functional Partners:
PIP5K1A
PIPK domain-containing protein.
  
 
0.959
PIP5K1C
Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma.
   
  0.937
INPP5E
Inositol polyphosphate-5-phosphatase E.
     
 0.934
PI4KA
Phosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family.
   
 0.932
PIP4K2A
Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha.
    
0.930
ARF6
ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.
    
 0.930
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
    
0.929
PLCE1
Phosphoinositide phospholipase C.
   
 0.922
PI4KB
Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family.
   
 0.919
SACM1L
SAC1 like phosphatidylinositide phosphatase.
    
 0.905
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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