STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PHF24PHD finger protein 24. (400 aa)    
Predicted Functional Partners:
FAM184B
Family with sequence similarity 184 member B.
      
 0.629
PDK2
Protein-serine/threonine kinase.
      
 0.594
IQCA1L
IQ motif containing with AAA domain 1 like.
      
 0.580
PHF21A
PHD finger protein 21A.
   
  
 0.578
YIPF5
Protein YIPF.
      
 0.554
MYADML2
Myeloid associated differentiation marker like 2.
      
 0.549
ITGB1BP2
Integrin subunit beta 1 binding protein 2.
      
 0.545
NCAPG
Non-SMC condensin I complex subunit G.
      
 0.520
P2RX6
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
      
 0.516
CACNG2
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
  
 0.480
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.