STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKIB1RBR-type E3 ubiquitin transferase. (1092 aa)    
Predicted Functional Partners:
GATAD1
GATA zinc finger domain containing 1.
 
 
  
 0.733
SAE1
SUMO1 activating enzyme subunit 1.
   
  
 0.614
ZNF292
Zinc finger protein 292.
   
 
 0.541
PTP4A2
Protein tyrosine phosphatase 4A2.
   
 
 0.485
CAMSAP1
Calmodulin regulated spectrin associated protein 1.
   
  
 0.485
TLK2
Tousled like kinase 2.
   
  
 0.474
RNF216
Ring finger protein 216.
   
 
 0.470
TULP4
Tubby like protein 4; Belongs to the TUB family.
   
  
 0.456
METTL9
Methyltransferase like 9.
   
  
 0.435
MED13L
Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
  
 0.419
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.