STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CAPN11Calpain 11; Belongs to the peptidase C2 family. (612 aa)    
Predicted Functional Partners:
CAST
Calpastatin.
   
 0.818
CAPN12
Calpain 12; Belongs to the peptidase C2 family.
  
 
0.771
CAPNS1
Calpain small subunit 1.
   
 0.639
BAK1
BCL2 antagonist/killer 1.
   
 0.632
SPATS1
Spermatogenesis associated serine rich 1.
      
 0.572
MAMLD1
Mastermind like domain containing 1.
    
 
 0.571
ZFP92
ZFP92 zinc finger protein.
    
 
 0.551
TKTL1
Transketolase like 1.
   
  
 0.537
BAX
BCL2 associated X, apoptosis regulator.
   
 0.531
CDK5R1
Cyclin-dependent kinase 5 activator.
   
  0.517
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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