STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DMRT1Doublesex and mab-3 related transcription factor 1. (378 aa)    
Predicted Functional Partners:
MSH4
MutS homolog 4.
   
 
 0.835
CYP19A1
Aromatase; A cytochrome P450 monooxygenase that catalyzes the conversion of C19 androgens, androst-4-ene-3,17-dione (androstenedione) and testosterone to the C18 estrogens, estrone and estradiol, respectively. Catalyzes three successive oxidations of C19 androgens: two conventional oxidations at C19 yielding 19-hydroxy and 19-oxo/19- aldehyde derivatives, followed by a third oxidative aromatization step that involves C1-beta hydrogen abstraction combined with cleavage of the C10-C19 bond to yield a phenolic A ring and formic acid. Alternatively, the third oxidative reaction yields a 19 [...]
    
 
 0.828
STRA8
Stimulated by retinoic acid 8.
   
  
 0.809
TNP1
Transition protein 1.
      
 0.807
LOC102152531
Cor1 domain-containing protein.
    
 
 0.708
LOC100687249
Cor1 domain-containing protein.
    
 
 0.708
RSPO1
R-spondin 1.
      
 0.707
SOX8
SRY-box 8.
   
 
 0.700
ZBTB16
Zinc finger and BTB domain containing 16.
    
 
 0.696
IP6K1
Kinase; Belongs to the inositol phosphokinase (IPK) family.
      
 0.687
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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