STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DMRT3Doublesex and mab-3 related transcription factor 3. (473 aa)    
Predicted Functional Partners:
DMRT2
Doublesex and mab-3 related transcription factor 2.
   
  
 0.846
DCTN3
Dynactin subunit 3.
      
 0.689
CNTN3
Contactin 3.
      
 0.679
FAM219A
Family with sequence similarity 219 member A.
      
 0.629
MSTN
Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.
      
 0.597
LASP1
LIM and SH3 protein 1.
      
 0.595
RPP25L
Alba domain-containing protein.
      
 0.591
NPSR1
Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
   
 
 0.570
MEGF11
Multiple EGF like domains 11.
      
 0.552
KANK1
KN motif and ankyrin repeat domains 1.
      
 0.543
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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