STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)    
Predicted Functional Partners:
NPLOC4
NPL4 homolog, ubiquitin recognition factor.
   
 0.998
NSFL1C
NSFL1 cofactor.
   
 0.998
UBXN6
UBX domain protein 6.
   
 0.997
C11H9orf72
Chromosome 11 C9orf72 homolog.
   
  
 0.996
UBXN4
UBX domain protein 4.
   
 0.996
UBXN1
UBX domain protein 1.
   
 0.994
UBXN7
UBX domain-containing protein 7.
   
 0.993
UFD1
Ubiquitin recognition factor in ER associated degradation 1.
   
 0.993
DERL1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 0.985
VCPKMT
Valosin containing protein lysine methyltransferase.
   
 0.980
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.