STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PIGOPhosphatidylinositol glycan anchor biosynthesis class O. (1154 aa)    
Predicted Functional Partners:
PIGF
Phosphatidylinositol glycan anchor biosynthesis class F.
    
 0.976
NCBP2
Mannosyltransferase.
     
 0.961
PIGG
Phosphatidylinositol glycan anchor biosynthesis class G.
   
 0.955
PIGB
Mannosyltransferase.
   
 
 0.947
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
    
 0.746
PIGQ
Phosphatidylinositol glycan anchor biosynthesis class Q.
      
 0.734
PIGC
Phosphatidylinositol glycan anchor biosynthesis class C.
      
 0.716
ENSCAFP00000058971
Uncharacterized protein.
      
 0.707
PIGV
GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.
   
 0.684
PIGT
Phosphatidylinositol glycan anchor biosynthesis class T.
    
 0.660
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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