STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIGOPhosphatidylinositol glycan anchor biosynthesis class O. (1154 aa)    
Predicted Functional Partners:
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
    
 0.969
PIGB
Mannosyltransferase.
    
 0.961
PIGS
Phosphatidylinositol glycan anchor biosynthesis class S.
   
 0.957
PIGT
Phosphatidylinositol glycan anchor biosynthesis class T.
    
 0.954
PIGF
Phosphatidylinositol glycan anchor biosynthesis class F.
    
 0.947
PIGU
Phosphatidylinositol glycan anchor biosynthesis class U.
   
 0.947
NCBP2
Mannosyltransferase.
    
 
 0.802
TMEM165
Transmembrane protein 165.
      
 0.694
MPDU1
Mannose-P-dolichol utilization defect 1.
      
 0.685
B4GALT6
Beta-1,4-galactosyltransferase 6.
   
  
 0.685
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.