SUPT3H protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SUPT3H

SPT3 homolog, SAGA and STAGA complex component. (405 aa)

Predicted Functional Partners:

TADA2B

0.963

ATXN7L3

0.961

SGF29

0.957

TADA2A

0.952

TAF10

0.949

TAF6L

0.948

TRRAP

0.948

SUPT7L

0.944

SF3B3

0.942

TADA3

0.936

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATXN7L3	SF3B3	ENSCAFP00000021066	ENSCAFP00000029880	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Splicing factor 3b subunit 3.	0.859
ATXN7L3	SGF29	ENSCAFP00000021066	ENSCAFP00000025225	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	SAGA complex associated factor 29.	0.986
ATXN7L3	SUPT3H	ENSCAFP00000021066	ENSCAFP00000002947	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	SPT3 homolog, SAGA and STAGA complex component.	0.961
ATXN7L3	SUPT7L	ENSCAFP00000021066	ENSCAFP00000032684	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	BTP domain-containing protein.	0.966
ATXN7L3	TADA2A	ENSCAFP00000021066	ENSCAFP00000026800	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcriptional adapter.	0.901
ATXN7L3	TADA2B	ENSCAFP00000021066	ENSCAFP00000046319	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcriptional adaptor 2B.	0.992
ATXN7L3	TADA3	ENSCAFP00000021066	ENSCAFP00000031654	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcriptional adaptor 3.	0.994
ATXN7L3	TAF10	ENSCAFP00000021066	ENSCAFP00000009728	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	0.996
ATXN7L3	TAF6L	ENSCAFP00000021066	ENSCAFP00000022995	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	TATA-box binding protein associated factor 6 like.	0.990
ATXN7L3	TRRAP	ENSCAFP00000021066	ENSCAFP00000045167	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	0.997
SF3B3	ATXN7L3	ENSCAFP00000029880	ENSCAFP00000021066	Splicing factor 3b subunit 3.	Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]	0.859
SF3B3	SGF29	ENSCAFP00000029880	ENSCAFP00000025225	Splicing factor 3b subunit 3.	SAGA complex associated factor 29.	0.950
SF3B3	SUPT3H	ENSCAFP00000029880	ENSCAFP00000002947	Splicing factor 3b subunit 3.	SPT3 homolog, SAGA and STAGA complex component.	0.942
SF3B3	SUPT7L	ENSCAFP00000029880	ENSCAFP00000032684	Splicing factor 3b subunit 3.	BTP domain-containing protein.	0.888
SF3B3	TADA2A	ENSCAFP00000029880	ENSCAFP00000026800	Splicing factor 3b subunit 3.	Transcriptional adapter.	0.948
SF3B3	TADA2B	ENSCAFP00000029880	ENSCAFP00000046319	Splicing factor 3b subunit 3.	Transcriptional adaptor 2B.	0.912
SF3B3	TADA3	ENSCAFP00000029880	ENSCAFP00000031654	Splicing factor 3b subunit 3.	Transcriptional adaptor 3.	0.851
SF3B3	TAF10	ENSCAFP00000029880	ENSCAFP00000009728	Splicing factor 3b subunit 3.	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	0.747
SF3B3	TAF6L	ENSCAFP00000029880	ENSCAFP00000022995	Splicing factor 3b subunit 3.	TATA-box binding protein associated factor 6 like.	0.929
SF3B3	TRRAP	ENSCAFP00000029880	ENSCAFP00000045167	Splicing factor 3b subunit 3.	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	0.853