STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENPP5Ectonucleotide pyrophosphatase/phosphodiesterase family member 5. (477 aa)    
Predicted Functional Partners:
COASY
Coenzyme A synthase.
   
 
  0.667
LRRC4
Leucine rich repeat containing 4.
    
 0.630
IYD
Iodotyrosine deiodinase.
  
  
 0.617
FHIT
Bis(5'-adenosyl)-triphosphatase.
     
 0.608
ASMTL
Acetylserotonin O-methyltransferase like.
     
  0.605
ZBED2
Zinc finger BED-type containing 2.
      
 0.600
STK33
Serine/threonine kinase 33.
      
 0.599
PTPRU
Protein tyrosine phosphatase receptor type U.
      
 0.596
PANK4
4'-phosphopantetheine phosphatase; May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels. The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'- phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway.
     
  0.595
SORCS3
Sortilin related VPS10 domain containing receptor 3.
      
 0.593
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.