STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TDRD6Tudor domain containing 6. (2106 aa)    
Predicted Functional Partners:
PDILT
Protein disulfide isomerase like, testis expressed.
   
 
 0.834
DIP2C
Disco interacting protein 2 homolog C.
      
 0.829
TACC2
Transforming acidic coiled-coil containing protein 2.
      
 0.825
PIWIL2
Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family.
   
 
 0.775
DLGAP2
DLG associated protein 2.
   
  
 0.750
USP4
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
      
 0.740
FAM83G
Family with sequence similarity 83 member G.
      
 0.698
WDFY4
WDFY family member 4.
      
 0.695
PIWIL1
Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family.
   
 
 0.685
PIWIL3
Piwi like RNA-mediated gene silencing 3; Belongs to the argonaute family.
   
 
 0.605
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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