STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RUSC2RUN and SH3 domain containing 2. (1512 aa)    
Predicted Functional Partners:
ATG9A
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
   
 
 0.819
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2.
      
 0.818
AP4S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
  
 0.810
TEPSIN
TEPSIN adaptor related protein complex 4 accessory protein.
      
 0.807
SERINC1
Serine incorporator 1.
      
 0.806
AP4E1
Adaptor related protein complex 4 subunit epsilon 1.
      
 0.787
DAGLB
Diacylglycerol lipase beta.
      
 0.783
SERINC3
Serine incorporator 3.
      
 0.781
MVD
Mevalonate diphosphate decarboxylase.
  
 0.747
ABCG4
ATP binding cassette subfamily G member 4.
      
 0.745
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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