STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLPP6Phospholipid phosphatase 6. (309 aa)    
Predicted Functional Partners:
ATP12A
Sodium/potassium-transporting ATPase subunit alpha.
      
 0.705
BCO1
Beta-carotene oxygenase 1.
      
 0.687
GPR182
G protein-coupled receptor 182; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.677
LPIN2
Lipin 2.
      
 0.610
ATP1A3
ATPase Na+/K+ transporting subunit alpha 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
      
 0.598
SMPD3
Sphingomyelin phosphodiesterase 3.
      
 0.593
SUCO
SUN domain containing ossification factor.
      
 0.580
TMED5
Transmembrane p24 trafficking protein 5.
      
 0.530
ADCY8
Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
      
 0.529
ATP1A4
Sodium/potassium-transporting ATPase subunit alpha.
      
 0.519
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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