STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CA9Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. (461 aa)    
Predicted Functional Partners:
CA12
Carbonic anhydrase 12; Belongs to the alpha-carbonic anhydrase family.
  
  
0.630
CA4
Carbonic anhydrase 4; Belongs to the alpha-carbonic anhydrase family.
  
  
0.620
RPF2
Ribosome production factor 2 homolog.
   
 
 0.599
HIF1A
Uncharacterized protein.
   
 
 0.585
CD1A8
Ig-like domain-containing protein.
   
  
 0.572
CA14
Carbonic anhydrase 14; Belongs to the alpha-carbonic anhydrase family.
  
 
0.548
RRS1
Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.
   
 
 0.509
SLC2A1
Solute carrier family 2, facilitated glucose transporter member 4; Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell.
   
  
 0.502
GRWD1
Glutamate rich WD repeat containing 1.
   
  
 0.487
BNIP3
BCL2 interacting protein 3.
   
  
 0.486
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.