STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCK2Cytoplasmic protein. (380 aa)    
Predicted Functional Partners:
NCK1
Cytoplasmic protein.
  
 
0.994
EFNB2
Ephrin B2; Belongs to the ephrin family.
    
 0.989
PAK2
Non-specific serine/threonine protein kinase.
    
 0.987
EFNB1
Ephrin B1.
   
 0.980
PAK3
P21 (RAC1) activated kinase 3.
    
 0.979
PAK1
Non-specific serine/threonine protein kinase.
    
 0.979
LCP2
Lymphocyte cytosolic protein 2.
    
 0.968
WIPF1
WAS/WASL interacting protein family member 1.
    
 0.957
PAK6
Non-specific serine/threonine protein kinase.
    
 0.956
PAK4
Non-specific serine/threonine protein kinase.
    
 0.956
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.