Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ASB4Ankyrin repeat and SOCS box containing 4. (427 aa)    
Predicted Functional Partners:
CHRAC1
Chromatin accessibility complex subunit 1.
      
 0.810
HIF1AN
Hypoxia inducible factor 1 subunit alpha inhibitor.
    
 
 0.780
CUL5
Cullin 5; Belongs to the cullin family.
    
 0.769
DNAJB5
DnaJ heat shock protein family (Hsp40) member B5.
   
   0.746
WDR6
WD repeat domain 6.
   
 
 0.661
ASB15
Ankyrin repeat and SOCS box containing 15.
  
  
0.615
RYR3
Ryanodine receptor 3.
   
 
 0.609
COPG2
Coatomer protein complex subunit gamma 2.
    
 
 0.605
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3.
    
 
 0.598
TRAPPC9
Trafficking protein particle complex 9.
    
 
 0.596
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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