STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLN1Talin 1. (2558 aa)    
Predicted Functional Partners:
VCL
Vinculin.
   
 0.999
PXN
Paxillin.
   
 0.996
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.984
PXN-2
Uncharacterized protein.
   
 
 0.981
PIP5K1C
Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma.
   
 0.962
APBB1IP
Amyloid beta precursor protein binding family B member 1 interacting protein.
   
 0.961
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.941
CAPN2
Calpain 2; Belongs to the peptidase C2 family.
   
 0.926
ITGA2B
Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.
   
 0.917
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.912
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.