STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RFX8RFX family member 8, lacking RFX DNA binding domain. (578 aa)    
Predicted Functional Partners:
PIGQ
Phosphatidylinositol glycan anchor biosynthesis class Q.
      
 0.857
OR28H03
Olfactory receptor.
      
 0.850
THOC1
THO complex 1.
      
 0.833
LLPH
LLP homolog, long-term synaptic facilitation factor.
      
 0.832
LRRTM4
Leucine rich repeat transmembrane neuronal 4.
      
 0.816
ASIC2
Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
    
 
 0.744
ACSS3
Acyl-CoA synthetase short chain family member 3.
      
 0.641
RFX5
Regulatory factor X5.
      
 0.611
MSRB3
Methionine sulfoxide reductase B3.
      
 0.597
MEIS1
Meis homeobox 1.
      
 0.595
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.