STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CEP135Centrosomal protein 135. (1139 aa)    
Predicted Functional Partners:
PLK4
Polo like kinase 4.
   
 
 0.895
CENPJ
Centromere protein J.
   
 
 0.895
PLK1
Serine/threonine-protein kinase PLK.
    
 0.881
WRAP73
WD repeat containing, antisense to TP73.
    
 
 0.877
STIL
STIL centriolar assembly protein.
   
 0.853
SASS6
SAS-6 centriolar assembly protein.
   
 
 0.844
CNTRL
Centriolin.
   
 
 0.837
CEP164
Centrosomal protein 164.
    
 
 0.836
CEP290
Centrosomal protein 290.
   
 
 0.811
CEP250
Centrosomal protein 250.
   
 
 0.807
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.