STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CREB3cAMP responsive element binding protein 3. (353 aa)    
Predicted Functional Partners:
CREB3L1
cAMP responsive element binding protein 3 like 1.
    
0.949
CREB3L3
cAMP responsive element binding protein 3 like 3.
    
 0.949
CREB3L4
cAMP responsive element binding protein 3 like 4.
    
 0.948
CREBRF
CREB3 regulatory factor.
    
 0.947
CREB1
cAMP responsive element binding protein 1.
    
 0.933
ATF1
Activating transcription factor 1.
    
 0.930
CREB5
cAMP responsive element binding protein 5.
    
 0.930
TAF4
TATA-box binding protein associated factor 4.
    
 0.921
CREM
cAMP-responsive element modulator; Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Tau is a transcriptional activator. Plays a role in spermatogenesis and is involved in spermatid maturation (By similarity).
    
 0.916
ATF6B
Activating transcription factor 6 beta.
    
 0.912
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.