node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATIC | GLUL | ENSCAFP00000021114 | ENSCAFP00000019307 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Glutamine synthetase; Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity). Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity). Essential for proliferation of fetal skin fibroblasts. Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating [...] | 0.622 |
ATIC | LOC100856570 | ENSCAFP00000021114 | ENSCAFP00000013625 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
ATIC | LOC487740 | ENSCAFP00000021114 | ENSCAFP00000036914 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.995 |
ATIC | PPAT | ENSCAFP00000021114 | ENSCAFP00000003241 | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.942 |
CAD | GFPT1 | ENSCAFP00000039642 | ENSCAFP00000004897 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutamine--fructose-6-phosphate transaminase 1. | 0.928 |
CAD | GFPT2 | ENSCAFP00000039642 | ENSCAFP00000050527 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutamine-fructose-6-phosphate transaminase 2. | 0.928 |
CAD | GLUL | ENSCAFP00000039642 | ENSCAFP00000019307 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutamine synthetase; Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity). Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity). Essential for proliferation of fetal skin fibroblasts. Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating [...] | 0.956 |
CAD | LOC100856570 | ENSCAFP00000039642 | ENSCAFP00000013625 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.765 |
CAD | LOC487740 | ENSCAFP00000039642 | ENSCAFP00000036914 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.765 |
CAD | PPAT | ENSCAFP00000039642 | ENSCAFP00000003241 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.975 |
ENSCAFP00000056413 | LOC100856570 | ENSCAFP00000056413 | ENSCAFP00000013625 | Pribosyltran_N domain-containing protein. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.493 |
ENSCAFP00000056413 | LOC487740 | ENSCAFP00000056413 | ENSCAFP00000036914 | Pribosyltran_N domain-containing protein. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.493 |
ENSCAFP00000056413 | PPAT | ENSCAFP00000056413 | ENSCAFP00000003241 | Pribosyltran_N domain-containing protein. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.938 |
ENSCAFP00000056413 | PRPS2 | ENSCAFP00000056413 | ENSCAFP00000017154 | Pribosyltran_N domain-containing protein. | Phosphoribosyl pyrophosphate synthetase 2. | 0.900 |
ENSCAFP00000066135 | GLUL | ENSCAFP00000066135 | ENSCAFP00000019307 | MGS domain-containing protein. | Glutamine synthetase; Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (By similarity). Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity). Essential for proliferation of fetal skin fibroblasts. Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating [...] | 0.622 |
ENSCAFP00000066135 | LOC100856570 | ENSCAFP00000066135 | ENSCAFP00000013625 | MGS domain-containing protein. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.995 |
ENSCAFP00000066135 | LOC487740 | ENSCAFP00000066135 | ENSCAFP00000036914 | MGS domain-containing protein. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.995 |
ENSCAFP00000066135 | PPAT | ENSCAFP00000066135 | ENSCAFP00000003241 | MGS domain-containing protein. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.936 |
GFPT1 | CAD | ENSCAFP00000004897 | ENSCAFP00000039642 | Glutamine--fructose-6-phosphate transaminase 1. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.928 |
GFPT1 | GFPT2 | ENSCAFP00000004897 | ENSCAFP00000050527 | Glutamine--fructose-6-phosphate transaminase 1. | Glutamine-fructose-6-phosphate transaminase 2. | 0.901 |