STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPDC1Protein tyrosine phosphatase domain containing 1. (790 aa)    
Predicted Functional Partners:
IPPK
Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
   
  
 0.879
ZNF462
Zinc finger protein 462.
   
  
 0.789
ERCC6L
ERCC excision repair 6 like, spindle assembly checkpoint helicase.
   
  
 0.787
CCDC73
Coiled-coil domain containing 73.
   
  
 0.769
KLK9
Kallikrein-related peptidase 9; Belongs to the peptidase S1 family.
      
 0.769
DRD5
Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.
      
 0.708
KIF20A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.685
SETD2
SET domain containing 2, histone lysine methyltransferase.
   
 
 0.683
GPER1
G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.682
CYP8B1
Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family.
   
  
 0.607
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.