STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GCM1Glial cells missing transcription factor 1. (435 aa)    
Predicted Functional Partners:
GCM2
Glial cells missing transcription factor 2.
     
 0.884
SYDE1
Synapse defective Rho GTPase homolog 1.
      
 0.692
TFAP2C
Transcription factor AP-2 gamma.
      
 0.645
FBXW2
F-box and WD repeat domain containing 2.
    
 
 0.629
HTRA4
HtrA serine peptidase 4.
    
 
 0.629
HTRA1
HtrA serine peptidase 1.
    
 
 0.629
CRYAB
Crystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
      
 0.611
HOPX
HOP homeobox.
    
 
 0.611
S100B
Protein S100; Belongs to the S-100 family.
      
 0.602
CHAF1B
Chromatin assembly factor 1 subunit B.
      
 0.591
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.