| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDC42 | CDC42-2 | ENSCAFP00000021684 | ENSCAFP00000060180 | Cell division cycle 42. | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | 0.801 |
| CDC42 | FGD1 | ENSCAFP00000021684 | ENSCAFP00000048099 | Cell division cycle 42. | FYVE, RhoGEF and PH domain containing 1. | 0.813 |
| CDC42 | FGD3 | ENSCAFP00000021684 | ENSCAFP00000003318 | Cell division cycle 42. | FYVE, RhoGEF and PH domain containing 3. | 0.777 |
| CDC42 | FGD4 | ENSCAFP00000021684 | ENSCAFP00000063396 | Cell division cycle 42. | FYVE, RhoGEF and PH domain containing 4. | 0.628 |
| CDC42 | J9P730_CANLF | ENSCAFP00000021684 | ENSCAFP00000041464 | Cell division cycle 42. | Uncharacterized protein. | 0.801 |
| CDC42 | VAV1 | ENSCAFP00000021684 | ENSCAFP00000027443 | Cell division cycle 42. | Vav guanine nucleotide exchange factor 1. | 0.899 |
| CDC42-2 | CDC42 | ENSCAFP00000060180 | ENSCAFP00000021684 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Cell division cycle 42. | 0.801 |
| CDC42-2 | FGD1 | ENSCAFP00000060180 | ENSCAFP00000048099 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | FYVE, RhoGEF and PH domain containing 1. | 0.883 |
| CDC42-2 | FGD3 | ENSCAFP00000060180 | ENSCAFP00000003318 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | FYVE, RhoGEF and PH domain containing 3. | 0.860 |
| CDC42-2 | FGD4 | ENSCAFP00000060180 | ENSCAFP00000063396 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | FYVE, RhoGEF and PH domain containing 4. | 0.767 |
| CDC42-2 | J9P730_CANLF | ENSCAFP00000060180 | ENSCAFP00000041464 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Uncharacterized protein. | 0.801 |
| CDC42-2 | VAV1 | ENSCAFP00000060180 | ENSCAFP00000027443 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | Vav guanine nucleotide exchange factor 1. | 0.947 |
| FGD1 | CDC42 | ENSCAFP00000048099 | ENSCAFP00000021684 | FYVE, RhoGEF and PH domain containing 1. | Cell division cycle 42. | 0.813 |
| FGD1 | CDC42-2 | ENSCAFP00000048099 | ENSCAFP00000060180 | FYVE, RhoGEF and PH domain containing 1. | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] | 0.883 |
| FGD1 | FGD3 | ENSCAFP00000048099 | ENSCAFP00000003318 | FYVE, RhoGEF and PH domain containing 1. | FYVE, RhoGEF and PH domain containing 3. | 0.931 |
| FGD1 | FGD4 | ENSCAFP00000048099 | ENSCAFP00000063396 | FYVE, RhoGEF and PH domain containing 1. | FYVE, RhoGEF and PH domain containing 4. | 0.680 |
| FGD1 | GNG12 | ENSCAFP00000048099 | ENSCAFP00000041436 | FYVE, RhoGEF and PH domain containing 1. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.896 |
| FGD1 | GNG14 | ENSCAFP00000048099 | ENSCAFP00000060405 | FYVE, RhoGEF and PH domain containing 1. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.808 |
| FGD1 | J9NYK5_CANLF | ENSCAFP00000048099 | ENSCAFP00000038374 | FYVE, RhoGEF and PH domain containing 1. | Uncharacterized protein. | 0.813 |
| FGD1 | J9P730_CANLF | ENSCAFP00000048099 | ENSCAFP00000041464 | FYVE, RhoGEF and PH domain containing 1. | Uncharacterized protein. | 0.813 |
