STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MITD1Microtubule interacting and trafficking domain containing 1. (249 aa)    
Predicted Functional Partners:
CHMP1A
Charged multivesicular body protein 1A.
    
 
 0.879
CHMP2A
Charged multivesicular body protein 2A.
   
 
 0.789
ENSCAFP00000053050
Uncharacterized protein.
   
 
 0.747
CHMP5
Uncharacterized protein.
   
 
 0.747
PGLYRP1
Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity.
      
 0.692
TMEM121
Transmembrane protein 121.
      
 0.664
IDS
Iduronate 2-sulfatase.
      
 0.557
TXNDC9
Thioredoxin domain containing 9.
   
  
 0.539
IST1
IST1 factor associated with ESCRT-III.
      
 0.527
EIF5B
Eukaryotic translation initiation factor 5B.
      
 0.526
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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