STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM83BFamily with sequence similarity 83 member B. (1015 aa)    
Predicted Functional Partners:
TINAGL1
Tubulointerstitial nephritis antigen like 1; Belongs to the peptidase C1 family.
      
 0.834
PRIM2
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
      
 0.811
RNF144B
RBR-type E3 ubiquitin transferase.
      
 0.810
TTC6
Tetratricopeptide repeat domain 6.
      
 0.792
PEF1
Penta-EF-hand domain containing 1.
      
 0.782
REC114
REC114 meiotic recombination protein.
      
 0.700
STXBP6
Syntaxin binding protein 6.
      
 0.698
GFRAL
GDNF family receptor alpha like.
   
  
 0.685
FAM83D
Family with sequence similarity 83 member D.
     
0.646
HBEGF
Heparin binding EGF like growth factor.
  
 
  0.622
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.