STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM83BFamily with sequence similarity 83 member B. (1015 aa)    
Predicted Functional Partners:
TINAGL1
Tubulointerstitial nephritis antigen like 1; Belongs to the peptidase C1 family.
   
  
 0.827
PEF1
Penta-EF-hand domain containing 1.
      
 0.821
PRIM2
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
   
  
 0.786
RNF144B
RBR-type E3 ubiquitin transferase.
   
 
 0.783
TTC6
Tetratricopeptide repeat domain 6.
      
 0.737
GFRAL
GDNF family receptor alpha like.
   
  
 0.710
REC114
REC114 meiotic recombination protein.
      
 0.701
STXBP6
Syntaxin binding protein 6.
      
 0.684
CDKAL1
CDK5 regulatory subunit-associated protein 1-like 1.
      
 0.592
ZNF451
Zinc finger protein 451.
   
  
 0.574
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.