STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NOL8Nucleolar protein 8. (1138 aa)    
Predicted Functional Partners:
URB1
URB1 ribosome biogenesis 1 homolog.
   
 
 0.923
DDX10
RNA helicase.
   
 
 0.847
URB2
URB2 ribosome biogenesis homolog.
   
 
 0.839
IARS1
Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
    
 0.828
DDX51
DEAD-box helicase 51; Belongs to the DEAD box helicase family.
   
 
 0.823
WDR89
WD repeat domain 89.
    
   0.809
MPHOSPH10
U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family.
   
  
 0.710
RORB
RAR related orphan receptor B.
      
 0.610
WDR43
WD repeat domain 43.
   
   0.595
H6PD
Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase.
      
 0.595
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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