STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF274Zinc finger protein 274. (622 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
  0.907
NGFR
Nerve growth factor receptor.
   
 0.903
FANK1
Fibronectin type III and ankyrin repeat domains 1.
    
 
 0.799
TAF1B
TATA-box binding protein associated factor, RNA polymerase I subunit B.
      
 0.774
SOX14
SRY-box transcription factor 14.
    
 
 0.672
SOX3
SRY-box 3.
    
 
 0.592
PNMA1
PNMA family member 1.
   
 0.547
ANKRD11
Ankyrin repeat domain 11.
   
 
 0.544
SETDB1
SET domain bifurcated histone lysine methyltransferase 1.
   
 
 0.530
SOX4
Transcription factor SOX.
    
 
 0.519
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.