STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)    
Predicted Functional Partners:
PLXNB2
Plexin B2.
    
 0.959
PLXNB1
Plexin B1.
    
 0.888
PLXNB3
Plexin B3.
    
 0.888
SEMA4B
Semaphorin 4B; Belongs to the semaphorin family.
    
 0.845
SEMA4A
Semaphorin 4A; Belongs to the semaphorin family.
    
 0.741
PLXND1
Plexin D1.
    
 0.683
SEMA4G
Semaphorin 4G; Belongs to the semaphorin family.
     
  0.654
RRAS
RAS related.
    
 
 0.574
NRP1
Neuropilin 1.
    
 0.572
CHCHD6
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
    
 0.554
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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