STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCAF10DDB1 and CUL4 associated factor 10. (564 aa)    
Predicted Functional Partners:
DCAF5
DDB1 and CUL4 associated factor 5.
   
 
 0.755
CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family.
    
 
 0.719
NUDT12
Nudix hydrolase 12.
    
 
 0.708
DDB1
Damage specific DNA binding protein 1.
    
 0.704
KLHDC10
Kelch domain containing 10.
    
 
 0.677
CYP20A1
Cytochrome P450 family 20 subfamily A member 1.
      
 0.677
C9H17orf75
Chromosome 9 C17orf75 homolog.
      
 0.657
RAB3IP
RAB3A interacting protein.
      
 0.646
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 
 0.644
ERCC8
ERCC excision repair 8, CSA ubiquitin ligase complex subunit.
    
 0.625
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.