STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF444Zinc finger protein 444. (325 aa)    
Predicted Functional Partners:
EMC3
ER membrane protein complex subunit 3; Belongs to the EMC3 family.
      
 0.548
ASB5
Ankyrin repeat and SOCS box containing 5.
    
 
 0.526
PRLHR
Prolactin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.517
FUT7
Fucosyltransferase 7.
   
  
 0.499
SLC39A8
Solute carrier family 39 member 8.
      
 0.497
RBM4B
RNA binding motif protein 4B.
    
 
 0.495
FAM53B
Family with sequence similarity 53 member B.
      
 0.489
SPOPL
Speckle type BTB/POZ protein like.
   
 
 0.481
DAG1
Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...]
      
 0.480
ZGPAT
Zinc finger CCCH-type and G-patch domain containing.
      
 0.435
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.