NLRP9 protein (Canis lupus familiaris) - STRING interaction network

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Score

NLRP9

NLR family pyrin domain containing 9. (988 aa)

Predicted Functional Partners:

NLRP6

0.921

GSDMD

0.737

MEFV

0.732

CASP4

0.633

CASP12

0.633

OOEP

0.632

TMEM238

0.625

RFPL4A

0.622

CARD8

0.617

ZNF444

0.616

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CARD8	CASP12	ENSCAFP00000053507	ENSCAFP00000042646	Uncharacterized protein.	Caspase-12; Involved in the activation cascade of caspases responsible for apoptosis execution.	0.907
CARD8	CASP4	ENSCAFP00000053507	ENSCAFP00000031566	Uncharacterized protein.	Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...]	0.941
CARD8	GSDMD	ENSCAFP00000053507	ENSCAFP00000033873	Uncharacterized protein.	Gasdermin D.	0.952
CARD8	MEFV	ENSCAFP00000053507	ENSCAFP00000033373	Uncharacterized protein.	MEFV innate immuity regulator, pyrin.	0.576
CARD8	NLRP6	ENSCAFP00000053507	ENSCAFP00000009685	Uncharacterized protein.	NLR family pyrin domain containing 6.	0.741
CARD8	NLRP9	ENSCAFP00000053507	ENSCAFP00000003655	Uncharacterized protein.	NLR family pyrin domain containing 9.	0.617
CASP12	CARD8	ENSCAFP00000042646	ENSCAFP00000053507	Caspase-12; Involved in the activation cascade of caspases responsible for apoptosis execution.	Uncharacterized protein.	0.907
CASP12	CASP4	ENSCAFP00000042646	ENSCAFP00000031566	Caspase-12; Involved in the activation cascade of caspases responsible for apoptosis execution.	Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...]	0.991
CASP12	GSDMD	ENSCAFP00000042646	ENSCAFP00000033873	Caspase-12; Involved in the activation cascade of caspases responsible for apoptosis execution.	Gasdermin D.	0.991
CASP12	MEFV	ENSCAFP00000042646	ENSCAFP00000033373	Caspase-12; Involved in the activation cascade of caspases responsible for apoptosis execution.	MEFV innate immuity regulator, pyrin.	0.922
CASP12	NLRP6	ENSCAFP00000042646	ENSCAFP00000009685	Caspase-12; Involved in the activation cascade of caspases responsible for apoptosis execution.	NLR family pyrin domain containing 6.	0.662
CASP12	NLRP9	ENSCAFP00000042646	ENSCAFP00000003655	Caspase-12; Involved in the activation cascade of caspases responsible for apoptosis execution.	NLR family pyrin domain containing 9.	0.633
CASP4	CARD8	ENSCAFP00000031566	ENSCAFP00000053507	Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...]	Uncharacterized protein.	0.941
CASP4	CASP12	ENSCAFP00000031566	ENSCAFP00000042646	Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...]	Caspase-12; Involved in the activation cascade of caspases responsible for apoptosis execution.	0.991
CASP4	GSDMD	ENSCAFP00000031566	ENSCAFP00000033873	Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...]	Gasdermin D.	0.998
CASP4	MEFV	ENSCAFP00000031566	ENSCAFP00000033373	Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...]	MEFV innate immuity regulator, pyrin.	0.967
CASP4	NLRP6	ENSCAFP00000031566	ENSCAFP00000009685	Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...]	NLR family pyrin domain containing 6.	0.866
CASP4	NLRP9	ENSCAFP00000031566	ENSCAFP00000003655	Caspase-1 subunit p10; Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive. In apoptotic cells, cleaves SPHK2 which is released from cells and remains enzymatically active extracell [...]	NLR family pyrin domain containing 9.	0.633
GSDMD	CARD8	ENSCAFP00000033873	ENSCAFP00000053507	Gasdermin D.	Uncharacterized protein.	0.952
GSDMD	CASP12	ENSCAFP00000033873	ENSCAFP00000042646	Gasdermin D.	Caspase-12; Involved in the activation cascade of caspases responsible for apoptosis execution.	0.991