STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SVBPSmall vasohibin binding protein. (66 aa)    
Predicted Functional Partners:
VASH1
Vasohibin 1.
    
 
 0.977
VASH2
Vasohibin 2.
    
 
 0.953
TTL
Tubulin tyrosine ligase.
      
 0.887
MARK4
Non-specific serine/threonine protein kinase.
      
 0.652
MAP7D1
MAP7 domain containing 1.
      
 0.595
BCS1L
BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family.
      
 0.582
TCF25
Transcription factor 25; Belongs to the tubulin family.
    
 
 0.580
TTLL7
Tubulin tyrosine ligase like 7.
      
 0.577
MAP4
Microtubule-associated protein.
      
 0.545
SPAST
Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...]
      
 0.533
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.