Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ALG2ALG2 alpha-1,3/1,6-mannosyltransferase. (416 aa)    
Predicted Functional Partners:
ALG1
Glycos_transf_1 domain-containing protein.
   
 0.971
ALG11
ALG11 alpha-1,2-mannosyltransferase.
   
 0.922
PDCD6IP
Programmed cell death 6 interacting protein.
   
 
 0.842
GMPPB
GDP-mannose pyrophosphorylase B.
  
 0.777
YIPF6
Protein YIPF.
  
 0.776
MUS81
MUS81 structure-specific endonuclease subunit.
   
 
 0.754
FANCM
FA complementation group M.
   
 
 0.746
RFT1
Protein RFT1 homolog; May be involved in N-linked oligosaccharide assembly. Belongs to the RFT1 family.
   
 
 0.742
BLM
BLM RecQ like helicase.
    
 
 0.731
PMM2
Phosphomannomutase; Involved in the synthesis of the GDP-mannose and dolichol- phosphate-mannose required for a number of critical mannosyl transfer reactions.
   
 0.731
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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