STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPN1Epsin 1. (569 aa)    
Predicted Functional Partners:
EPN3
Epsin 3.
  
0.994
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
   
 0.991
EPS15
Epidermal growth factor receptor pathway substrate 15.
   
 0.990
EPN2
Epsin 2.
  
  
0.987
EGFR
Receptor protein-tyrosine kinase.
    
 0.983
CLTB
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
   
 0.965
NECAP2
NECAP endocytosis associated 2.
    
 0.933
ENSCAFP00000066138
DUF1681 domain-containing protein.
    
 0.933
CLINT1
Clathrin interactor 1.
     
0.913
ENTHD1
ENTH domain containing 1.
     
 
0.900
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.