STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
P3H1Prolyl 3-hydroxylase 1. (739 aa)    
Predicted Functional Partners:
CRTAP
Cartilage associated protein.
   
0.980
FKBP10
Peptidylprolyl isomerase.
   
  
 0.846
ENSCAFP00000056541
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 
 0.805
P3H4
Prolyl 3-hydroxylase family member 4 (non-enzymatic).
   
 
0.799
CEP290
Centrosomal protein 290.
      
 0.781
P4HA2
Prolyl 4-hydroxylase subunit alpha 2.
   
  
 0.776
PLOD1
Fe2OG dioxygenase domain-containing protein.
   
 
 0.775
NUDCD1
NudC domain containing 1.
    
   0.769
SLC26A2
Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
      
 0.758
P4HA1
Prolyl 4-hydroxylase subunit alpha 1.
   
  
 0.748
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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