STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPM1BProtein phosphatase, Mg2+/Mn2+ dependent 1B. (479 aa)    
Predicted Functional Partners:
ISG15
ISG15 ubiquitin like modifier.
   
 0.920
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
   
 0.913
GHRH
Growth hormone releasing hormone.
   
    0.825
PREPL
Prolyl endopeptidase like.
   
  
 0.727
PPM1A
Protein phosphatase, Mg2+/Mn2+ dependent 1A.
  
 
0.676
SLC3A1
Solute carrier family 3 member 1.
 
 
  
 0.617
GCSAM
Germinal center associated signaling and motility.
      
 0.557
CEP170
Centrosomal protein 170.
   
 
 0.545
USP38
Ubiquitin specific peptidase 38; Belongs to the peptidase C19 family.
   
 
 0.540
HERC5
HECT domain-containing protein.
    
  0.532
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.