Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STX17Syntaxin 17; Belongs to the syntaxin family. (345 aa)    
Predicted Functional Partners:
SNAP29
Synaptosome associated protein 29.
    
 0.999
VAMP8
Vesicle associated membrane protein 8.
    
 0.995
ATG14
Autophagy related 14.
   
 0.993
VAMP7
Vesicle associated membrane protein 7; Belongs to the synaptobrevin family.
   
 0.992
ENSCAFP00000055760
V-SNARE coiled-coil homology domain-containing protein.
    
 0.988
STX18
Syntaxin 18.
   
 0.978
STX5
Syntaxin 5; Belongs to the syntaxin family.
    
 0.977
VPS39
VPS39 subunit of HOPS complex.
   
 0.974
VTI1B
Vesicle transport through interaction with t-SNAREs 1B.
   
 0.974
STX8
Syntaxin 8.
    
 0.972
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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