STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADGRB3Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1523 aa)    
Predicted Functional Partners:
ELMO1
Engulfment and cell motility 1.
    
 0.825
PTPRE
Protein tyrosine phosphatase receptor type E.
    
 
 0.777
ELMO2
Engulfment and cell motility 2.
    
 0.774
RANBP2
RAN binding protein 2.
   
 
 0.771
SYNGAP1
Synaptic Ras GTPase activating protein 1.
   
 
 0.742
PPFIA2
PTPRF interacting protein alpha 2.
   
  
 0.708
SASH1
SAM and SH3 domain containing 1.
      
 0.683
ELMO3
Engulfment and cell motility 3.
    
 0.657
TMTC2
Transmembrane O-mannosyltransferase targeting cadherins 2.
      
 0.629
SERPINB7
Serpin family B member 7; Belongs to the serpin family.
      
 0.621
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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