STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GUCA2AGuanylate cyclase activator 2A. (111 aa)    
Predicted Functional Partners:
GUCY2C
Guanylate cyclase.
   
 0.998
GUCA2B
Guanylate cyclase activator 2B.
   
 
 0.990
TMIGD1
Transmembrane and immunoglobulin domain containing 1.
   
  
 0.918
CA2
Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family.
   
  
 0.747
EMD
Emerin.
      
 0.692
NPR3
Natriuretic peptide receptor 3.
   
 0.624
OTOP2
Otopetrin 2.
      
 0.592
CNGA3
Cyclic nucleotide-gated channel alpha 3.
      
 0.570
SUSD5
Sushi domain containing 5.
      
 0.563
SLC51B
Solute carrier family 51 beta subunit.
   
  
 0.555
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.