STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GUCA2AGuanylate cyclase activator 2A. (111 aa)    
Predicted Functional Partners:
GUCY2C
Guanylate cyclase.
   
 
 0.844
GUCA2B
Guanylate cyclase activator 2B.
   
  
 0.776
TMIGD1
Transmembrane and immunoglobulin domain containing 1.
   
  
 0.715
CLCA4
Chloride channel accessory 4.
   
  
 0.623
CHGB
Chromogranin B.
   
  
 0.616
TMEM82
Transmembrane protein 82.
   
  
 0.544
TMEM52
Transmembrane protein 52.
      
 0.515
LCT
Lactase.
   
  
 0.505
DCLK1
Doublecortin like kinase 1.
      
 0.499
AGA
Aspartylglucosaminidase.
   
  
 0.494
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.