STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIVEP3Human immunodeficiency virus type I enhancer binding protein 3. (2309 aa)    
Predicted Functional Partners:
GPR84
G protein-coupled receptor 84.
    
 
 0.810
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif 18.
      
 0.744
TAMM41
Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.
   
  
 0.700
PPT1
Palmitoyl-protein thioesterase 1.
      
 0.690
ARID4B
AT-rich interaction domain 4B.
    
 
 0.656
TET2
Tet methylcytosine dioxygenase 2.
      
 0.650
SELENOS
Selenoprotein S.
      
 0.612
MMS22L
MMS22 like, DNA repair protein.
      
 0.608
IRX3
Iroquois homeobox 3.
    
 0.608
TTC8
Tetratricopeptide repeat domain 8 isoform 1.
    
 
 0.604
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.