IL11 protein (Canis lupus familiaris) - STRING interaction network

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Score

IL11

Interleukin 11. (199 aa)

Predicted Functional Partners:

GALT

0.991

IL6

0.984

OSM

0.980

CTF1

0.978

LIF

0.971

IL13

0.951

IL6ST

0.947

IL6R

0.924

LIFR

0.905

CNTFR

0.894

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNTFR	CTF1	ENSCAFP00000002838	ENSCAFP00000024588	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	Uncharacterized protein.	0.923
CNTFR	GALT	ENSCAFP00000002838	ENSCAFP00000002871	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.	0.844
CNTFR	IL11	ENSCAFP00000002838	ENSCAFP00000003760	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	Interleukin 11.	0.894
CNTFR	IL13	ENSCAFP00000002838	ENSCAFP00000001250	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	Interleukin-13; Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages.	0.821
CNTFR	IL6	ENSCAFP00000002838	ENSCAFP00000053025	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.920
CNTFR	IL6R	ENSCAFP00000002838	ENSCAFP00000025308	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	Interleukin 6 receptor.	0.880
CNTFR	IL6ST	ENSCAFP00000002838	ENSCAFP00000062759	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	Uncharacterized protein.	0.956
CNTFR	LIF	ENSCAFP00000002838	ENSCAFP00000036140	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	LIF interleukin 6 family cytokine.	0.879
CNTFR	LIFR	ENSCAFP00000002838	ENSCAFP00000047973	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	Leukemia inhibitory factor receptor; Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells (By similarity).	0.986
CNTFR	OSM	ENSCAFP00000002838	ENSCAFP00000018361	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	Oncostatin M.	0.893
CTF1	CNTFR	ENSCAFP00000024588	ENSCAFP00000002838	Uncharacterized protein.	Ciliary neurotrophic factor receptor subunit alpha; Binds to CNTF. The alpha subunit provides the receptor specificity (By similarity).	0.923
CTF1	GALT	ENSCAFP00000024588	ENSCAFP00000002871	Uncharacterized protein.	Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.	0.897
CTF1	IL11	ENSCAFP00000024588	ENSCAFP00000003760	Uncharacterized protein.	Interleukin 11.	0.978
CTF1	IL13	ENSCAFP00000024588	ENSCAFP00000001250	Uncharacterized protein.	Interleukin-13; Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages.	0.883
CTF1	IL6	ENSCAFP00000024588	ENSCAFP00000053025	Uncharacterized protein.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.944
CTF1	IL6R	ENSCAFP00000024588	ENSCAFP00000025308	Uncharacterized protein.	Interleukin 6 receptor.	0.844
CTF1	IL6ST	ENSCAFP00000024588	ENSCAFP00000062759	Uncharacterized protein.	Uncharacterized protein.	0.955
CTF1	LIF	ENSCAFP00000024588	ENSCAFP00000036140	Uncharacterized protein.	LIF interleukin 6 family cytokine.	0.988
CTF1	LIFR	ENSCAFP00000024588	ENSCAFP00000047973	Uncharacterized protein.	Leukemia inhibitory factor receptor; Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells (By similarity).	0.989
CTF1	OSM	ENSCAFP00000024588	ENSCAFP00000018361	Uncharacterized protein.	Oncostatin M.	0.991