STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM86BTransmembrane protein 86B. (226 aa)    
Predicted Functional Partners:
TMEM86A
Transmembrane protein 86A.
  
  
0.907
ENPP6
Ectonucleotide pyrophosphatase/phosphodiesterase 6.
     
 0.905
PLA2G2E
Phospholipase A(2).
   
 
  0.889
LPCAT4
Lysophosphatidylcholine acyltransferase 4.
     
 0.886
GDPD1
Glycerophosphodiester phosphodiesterase domain containing 1.
     
 0.884
GDPD3
Glycerophosphodiester phosphodiesterase domain containing 3.
     
 0.884
ENPP2
Ectonucleotide pyrophosphatase/phosphodiesterase 2.
     
 0.883
PLA2G1B
Phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules; Belongs to the phospholipase A2 family.
   
 
  0.882
PLA2G2F
Phospholipase A(2).
   
 
  0.882
PLAAT3
Phospholipase A and acyltransferase 3.
   
 
  0.882
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.