STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RHOQRas homolog family member Q. (126 aa)    
Predicted Functional Partners:
EXOC7
Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
    
 0.976
RHOJ
Ras homolog family member J.
   
    0.933
CRK
CRK proto-oncogene, adaptor protein.
   
 
 0.927
TRIP10
Thyroid hormone receptor interactor 10.
    
 0.920
RAPGEF1
Rap guanine nucleotide exchange factor 1.
    
 0.908
CRKL
CRK like proto-oncogene, adaptor protein.
   
 
 0.893
GNA15
G protein subunit alpha 15.
   
 0.838
GOPC
Golgi associated PDZ and coiled-coil motif containing.
    
 0.792
TMEM247
Transmembrane protein 247.
      
 0.775
CDC42EP2
Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family.
    
 
 0.762
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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