MTO1 protein (Canis lupus familiaris) - STRING interaction network

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[Homology]

Score

MTO1

Mitochondrial tRNA translation optimization 1. (672 aa)

Predicted Functional Partners:

GTPBP3

0.974

TRMU

0.938

VPS45

0.900

TRIT1

0.884

MOCS3

0.865

CCDC127

0.772

MTFMT

0.714

XPNPEP1

0.702

AARS1

0.701

CSNK2A2

0.701

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AARS1	CCDC127	ENSCAFP00000029842	ENSCAFP00000016270	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.	Coiled-coil domain containing 127.	0.746
AARS1	CSNK2A2	ENSCAFP00000029842	ENSCAFP00000047707	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.	Casein kinase 2 alpha 2.	0.607
AARS1	MTO1	ENSCAFP00000029842	ENSCAFP00000003866	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.	Mitochondrial tRNA translation optimization 1.	0.701
AARS1	XPNPEP1	ENSCAFP00000029842	ENSCAFP00000046848	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.	X-prolyl aminopeptidase 1; Belongs to the peptidase M24B family.	0.672
CCDC127	AARS1	ENSCAFP00000016270	ENSCAFP00000029842	Coiled-coil domain containing 127.	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.	0.746
CCDC127	CSNK2A2	ENSCAFP00000016270	ENSCAFP00000047707	Coiled-coil domain containing 127.	Casein kinase 2 alpha 2.	0.753
CCDC127	MTO1	ENSCAFP00000016270	ENSCAFP00000003866	Coiled-coil domain containing 127.	Mitochondrial tRNA translation optimization 1.	0.772
CCDC127	XPNPEP1	ENSCAFP00000016270	ENSCAFP00000046848	Coiled-coil domain containing 127.	X-prolyl aminopeptidase 1; Belongs to the peptidase M24B family.	0.749
CSNK2A2	AARS1	ENSCAFP00000047707	ENSCAFP00000029842	Casein kinase 2 alpha 2.	Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family.	0.607
CSNK2A2	CCDC127	ENSCAFP00000047707	ENSCAFP00000016270	Casein kinase 2 alpha 2.	Coiled-coil domain containing 127.	0.753
CSNK2A2	MTO1	ENSCAFP00000047707	ENSCAFP00000003866	Casein kinase 2 alpha 2.	Mitochondrial tRNA translation optimization 1.	0.701
CSNK2A2	XPNPEP1	ENSCAFP00000047707	ENSCAFP00000046848	Casein kinase 2 alpha 2.	X-prolyl aminopeptidase 1; Belongs to the peptidase M24B family.	0.680
GTPBP3	MTFMT	ENSCAFP00000022668	ENSCAFP00000025216	GTP binding protein 3, mitochondrial.	Mitochondrial methionyl-tRNA formyltransferase.	0.414
GTPBP3	MTO1	ENSCAFP00000022668	ENSCAFP00000003866	GTP binding protein 3, mitochondrial.	Mitochondrial tRNA translation optimization 1.	0.974
GTPBP3	TRMU	ENSCAFP00000022668	ENSCAFP00000063762	GTP binding protein 3, mitochondrial.	tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase.	0.892
MOCS3	MTO1	ENSCAFP00000017036	ENSCAFP00000003866	Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]	Mitochondrial tRNA translation optimization 1.	0.865
MOCS3	TRMU	ENSCAFP00000017036	ENSCAFP00000063762	Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]	tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase.	0.503
MTFMT	GTPBP3	ENSCAFP00000025216	ENSCAFP00000022668	Mitochondrial methionyl-tRNA formyltransferase.	GTP binding protein 3, mitochondrial.	0.414
MTFMT	MTO1	ENSCAFP00000025216	ENSCAFP00000003866	Mitochondrial methionyl-tRNA formyltransferase.	Mitochondrial tRNA translation optimization 1.	0.714
MTFMT	TRIT1	ENSCAFP00000025216	ENSCAFP00000049177	Mitochondrial methionyl-tRNA formyltransferase.	tRNA isopentenyltransferase 1; Belongs to the IPP transferase family.	0.592