STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GTF2A1LUncharacterized protein. (476 aa)    
Predicted Functional Partners:
GTF2A1
General transcription factor IIA subunit 1.
    
0.988
ENSCAFP00000055325
TFIIA_gamma_C domain-containing protein.
    
 0.920
GTF2A2-2
TFIIA_gamma_N domain-containing protein.
    
 0.920
STON1
Stonin-1; May be involved in the endocytic machinery.
 
      0.900
TBP
TATA-box binding protein.
   
 0.884
GTF2A2
General transcription factor IIA subunit 2.
    
 0.881
STON2
Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family.
 
   
  0.779
GTF2B
General transcription factor IIB.
   
 
 0.754
GTF2E2
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
    
 
 0.722
TBPL2
TATA-box binding protein like 2.
   
 
 0.691
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (20%) [HD]